There is communication between microbiome in the gut and the brain and they go back and forth, a breakdown in the brain causes a breakdown in the microbiome and vice versa, both areas need to be addressed to balance them out. The 3 stresses that contribute to setting off the imbalance are chemical stress, physical stress and mental-emotional stress. 600% increase of pathogenic bacteria released, within hours, in your gut when you have a stress response, this results in a very sick microbiome and the microbial organ is then off, a high-stress response must be addressed to avoid this occurring and to assist in keeping a healthy brain/gut relationship.